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Effects of childhood trauma on BDNF and TBARS during crack-cocaine withdrawal

Objective To evaluate the association between childhood trauma (CT) and serum levels of brain-derived neurotrophic factor (BDNF) and thiobarbituric acid-reactive substances (TBARS) during crack-cocaine withdrawal. Acessar

The COVID-19 pandemic and its impact on substance use: Implications for prevention and treatment

The COVID-19 pandemic has brought major challenges to healthcare systems and public health policies globally, as it requires novel treatment and prevention strategies to adapt for the impact of the pandemic. Individuals with substance…

Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil

Suicide is a severe health problem, with high rates in individuals with addiction. Considering the lack of studies exploring suicide predictors in this population, we aimed to investigate factors associated…

Increased cortisol levels are associated with low treatment retention in crack cocaine users

Objective Our aim was to investigate the association between morning salivary cortisol levels and treatment retention in crack cocaine users. Acessar

Anger and substance abuse: a systematic review and meta-analysis

Objective Conduct a systematic review and meta-analysis to evaluate levels of anger among substance users compared to non-user controls and to analyze the possible association between anger and psychoactive substance…

Gender differences in progression to crack-cocaine use and the role of sexual and physical violence

OBJECTIVE: This study aimed to evaluate whether progression from first drug use to crack-cocaine use differs according to gender, and whether the report of sexual or physical violence impacts the time…

Assessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder

Objectives To evaluate the cognitive performance of individuals with alcohol (AUD) and/or crack cocaine use disorder (CUD) and polysubstance use using the MMSE and to investigate the impact of substance…

Serum BDNF levels increase during early drug withdrawal in alcohol and crack cocaine addiction

Abstract Brain-derived neurotrophic factor (BDNF) is involved in several drug-induced brain neuroadaptations. The impact of withdrawal from substances that have different neurological mechanisms on BDNF levels is unclear. Our goal…

Framing substance use as “recreational” is neither accurate nor helpful for prevention purposes

Abstract This debate paper discusses six reasons why the term “recreational substance use” should be avoided. (1) Social norms and beliefs are drivers of behavior; therefore, the normalized use of the term…

Racial-Based Bullying and Substance Use: a Brazilian National Cross-Sectional Survey Among Students

Abstract Racial discrimination has been associated with worse health status and risky health behavior. Understanding the relationship between racial-based bullying (RBB) — an overlap of bullying and interpersonal racial discrimination…

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